Name: Italian Penicillin Soup Recipe
Prep time: 10 min
Cook time: 45 min
Total time: 55 min
Cuisine: Italian
Ingredients: 8 cups lower-sodium chicken broth; 2 cups chopped sweet onion; 1 1/2 cups peeled and coarsely chopped carrots (about 2); 2 celery ribs, coarsely chopped; 6 garlic cloves, smashed and peeled; 3/4 teaspoon kosher salt; 4 thyme sprigs; 2 fresh bay leaves; 1 (2 ounce) Parmigiano-Reggiano cheese rind, plus grated cheese for garnish; 4 ounces uncooked pastina pasta; 2 cups shredded rotisserie chicken; Fresh flat-leaf parsley leaves for garnish

Jump to Recipe·5.2 from 19 reviews

If you’re craving a soup that feels like a warm hug and tastes like a culinary celebration, then you’re in for a treat with this Italian Penicillin Soup. This isn’t your everyday chicken noodle soup; it’s an extraordinary blend of fresh ingredients and rich, comforting flavors that truly soothe the soul. Made with tender shredded rotisserie chicken, delicate pastina pasta, and vibrant vegetables, all simmered in a fragrant chicken broth enriched with Parmigiano-Reggiano rind and fresh herbs, this soup is a delicious remedy you’ll want to make again and again.

Italian Penicillin Soup Recipe - Recipe Image

Ingredients You’ll Need

These straightforward ingredients might seem simple at first glance, but each one plays a vital role in building the deep, layered flavors and comforting textures of Italian Penicillin Soup. From the sweetness of the onions and carrots to the savory punch of the cheese rind, every component contributes to the dish’s ultimate deliciousness.

8 cups lower-sodium chicken broth: Acts as the flavorful, soothing base of the soup, allowing other ingredients to shine without being too salty.
2 cups chopped sweet onion: Adds a natural sweetness and aromatic depth that complements the broth perfectly.
1 1/2 cups peeled, coarsely chopped carrots (about 2): Brings color, subtle earthiness, and a touch of natural sweetness.
2 celery ribs, coarsely chopped: Infuses a gentle, fresh vegetal note that balances richness.
6 garlic cloves, smashed and peeled: Delivers warmth and a familiar savory kick without overpowering the dish.
3/4 teaspoon kosher salt: Enhances the natural flavors of the vegetables and broth.
4 thyme sprigs: Provide an earthy, herbal aroma that’s classic in Italian soups.
2 fresh bay leaves: Impart a gentle, herbal backdrop that rounds out the flavor profile.
1 (2 ounce) Parmigiano-Reggiano cheese rind, plus grated cheese for garnish: Adds umami and richness as it simmers, making the broth luxuriously flavorful.
4 ounces uncooked pastina pasta: Small, tender pasta that soaks up the broth and adds comforting texture.
2 cups shredded rotisserie chicken: Ready-to-use protein that blends into the soup, making it hearty yet effortless.
Fresh flat-leaf parsley leaves: Brighten the final dish with a fresh, vibrant touch as a garnish.

How to Make Italian Penicillin Soup

Step 1: Build Your Flavor Base

Start by gathering all your ingredients — having everything ready makes the process smooth and enjoyable. Bring the chicken broth, sweet onion, carrots, celery, garlic, and kosher salt to a lively boil in a large saucepan or a small Dutch oven. Then, reduce the heat to medium-low and let it simmer until those vegetables are meltingly tender, about 10 minutes. This step is where the soup’s comforting aroma begins to fill your kitchen — that’s your cue to cozy up to the stove.

Step 2: Blend for Velvety Goodness

Once the vegetables are soft, use a slotted spoon to transfer them along with 1 cup of the broth to a blender. Carefully secure the lid, removing the center piece to let steam escape, and cover that opening with a clean towel — safety first! Blend everything until smooth and silky, about 30 seconds. This puree is the secret star of Italian Penicillin Soup, bringing an irresistible creamy texture without any cream. Stir it right back into your pot, and you’ll instantly see the soup’s body transform.

Step 3: Add Herbs, Cheese Rind, and Pasta

Now it’s time for the herbs and that game-changing Parmigiano-Reggiano cheese rind. Toss in the thyme sprigs, bay leaves, and cheese rind, then bring the soup back up to a gentle boil. Add your pastina pasta and reduce the heat to medium-low. Stir occasionally and let the pasta cook until tender, about 18 to 20 minutes. The broth will thicken slightly and develop such a rich, layered flavor — truly the heart of the Italian Penicillin Soup experience.

Step 4: Finish with Chicken and Season to Taste

During the last 3 minutes of cooking, stir in the shredded rotisserie chicken so it warms through without drying out. Once the pasta is perfectly tender and the chicken heated, remove the pot from the heat, and carefully fish out the thyme sprigs, bay leaves, and cheese rind. Your soup is now ready to be served, but the finishing touches make all the difference.

How to Serve Italian Penicillin Soup

Garnishes

Fresh flat-leaf parsley is the classic garnish here; its bright green color and subtle herbal punch add a fresh finish that perfectly balances the soup’s richness. A generous sprinkle of freshly grated Parmigiano-Reggiano cheese right before serving enhances the soup’s savory depth and gives a lovely melted texture atop each steaming bowl.

Side Dishes

Italian Penicillin Soup shines on its own, but it also pairs beautifully with a simple rustic bread, such as a crusty baguette or garlic focaccia, perfect for dipping. A crisp green side salad with a tangy vinaigrette can add a refreshing contrast, making your meal feel both wholesome and complete.

Creative Ways to Present

If you want to impress friends or family, serve your Italian Penicillin Soup in charming mini crocks or even hollowed-out bread bowls for a cozy, rustic vibe. Adding a swirl of extra virgin olive oil or a sprinkle of chili flakes can personalize each bowl with a pop of color and flavor. You might even top it with a drizzle of pesto for a fragrant twist that keeps the Italian theme going strong.

Make Ahead and Storage

Storing Leftovers

Leftover Italian Penicillin Soup tastes just as wonderful the next day as the flavors have more time to meld. Store it in an airtight container in the refrigerator for up to 3 days. To keep the pasta from getting mushy, consider undercooking the pastina slightly if you know you’ll be storing leftovers.

Freezing

This soup freezes well, making it a perfect make-ahead meal on busy days. Freeze in portion-sized airtight containers, leaving some headspace as the soup expands. When ready to enjoy, thaw overnight in the refrigerator to maintain the best flavor and texture.

Reheating

Reheat Italian Penicillin Soup gently on the stovetop over low-medium heat, stirring occasionally. If the soup has thickened too much, add a splash of chicken broth or water to reach your preferred consistency. Avoid microwaving at high heat to keep that lovely creamy texture intact.

FAQs

Can I substitute the rotisserie chicken with homemade chicken?

Absolutely! Using homemade shredded chicken works wonderfully and gives you full control over seasoning. Just make sure the chicken is tender and cooked through to maintain the soup’s comforting quality.

What can I use if I don’t have pastina pasta?

If you don’t have pastina, feel free to substitute with other small pasta shapes like orzo, acini di pepe, or small ditalini. Just keep an eye on cooking times to avoid overcooking.

Is the Parmigiano-Reggiano rind essential?

While it’s not mandatory, the cheese rind is a fantastic addition that adds umami and richness to the broth. If unavailable, you can skip it or substitute with a Parmesan chunk if you have one.

Can I make this soup vegetarian?

To make a vegetarian version, use vegetable broth and omit the chicken. You might consider adding sautéed mushrooms or beans for protein and savoriness.

How spicy is Italian Penicillin Soup?

This soup is not spicy at all; it’s all about soothing, gentle, and deeply comforting flavors. However, you can always add a pinch of red pepper flakes to your bowl if you enjoy a little heat!

Final Thoughts

Trying Italian Penicillin Soup is like giving yourself a big, delicious dose of comfort and care. It’s vibrant enough to impress anyone at your table but also simple enough to whip up anytime you need something nourishing and soul-satisfying. Trust me, once you make this soup, it’s going to be your new go-to recipe for cozy nights and feel-good meals. Give it a try, and let the magic of Italian Penicillin Soup warm your heart and kitchen!